#myInput {
    width: 100%; /* Full-width */
    font-size: 15px; /* Increase font-size */
    padding: 12px 0 12px 15px; /* Add some padding */
    border: 1px solid #ddd; /* Add a grey border */
    border-radius: 10px
}

.fw700 {
    font-weight: 700;
}

.fhl-lastupdate {
    color: white;
    padding: 10px;
}

.fhl-logo {
    height: 200px;
}

.fhl-insight-title {
    color: white;
    font-size: 1.7em;
}

.fhl-insight-num {
    display: block;
    width: 100px;
    height: 100px;
    border-radius: 50%;
    background-color: #ef8784;
    color: #ffffff;
    font-size: 40px;
    line-height: 100px;
    margin: 0 auto;
}


.fhl-insight-description {
    color: #f2f2f2;
}

.fhl-insight2-img {
    height: 130px;
    width: 130px;
    padding: 30px;
}

.fhl-insight2-icon {
    background-color: white;
    font-size: 60px;
    padding: 40px;
}

.fhl-cite-file {
    background-color: white;
    font-size: 50px;
    padding: 10px 10px 10px 40px
}

.fhl-cite-citation {
    background-color: white;
    font-size: 50px;
    padding: 10px 20px;
}

.img-icon {
    height: 18px;
}


.border_blue th {
    font-size: 15px;
}

.border_blue td {
    font-size: 14px;
}

.border_blue tbody tr {
    border-left: solid 1px #ddd;
    border-right: solid 1px #ddd;
    border-bottom: solid 1px #ddd;
}

.border_blue thead {
    border-left: solid 3px #50cae2;
    border-right: solid 3px #50cae2;
}

.border_blue thead th {
    border-top: solid 3px #50cae2;
    border-bottom: none;
    background-color: #50cae2;
    color: white;
}

.border_blue tbody tr:hover td, .table-fixed_header tbody tr:hover th {
    background-color: #f1f1f1 !important;
}


.fixed_header tbody {
    display: block;
    width: 100%;
    overflow: auto;
    height: 600px;
}

.fixed_header thead tr {
    display: block;
}


/* MARK variables */
:root {

    --main-brand-color: #50cae2;
    --main-brand-color-embedded: #bdebf4;
    --second-brand-color: #50e2be;
    --second-brand-color-embedded: #bdf4e7;

    --white: #ffffff; /* 100 */
    --lightlightlight-grey: #f8f8f8; /* 97% */
    --lightlight-grey: #f2f2f2; /* 95% */
    --light-grey: #d9d9d9; /* 85% */
    --medium-grey: #b3b3b3; /* 70% */
    --mediumdark-grey: #808080; /* 50% */
    --dark-grey: #4d4d4d; /* 30% */
    --black: #404040; /* 25% */

    --red: #d9534f;
    --red-pastel: #f6d6d5;
    --orange-pastel: #ffe6cc;
    --green: #5cb85c;
    --green-pastel: #cae8ca;
    --lima-pastel: #e0fdc1;

}

/* MARK global changes */

/* Page */

@media (min-width: 1694px) {
    .container {
        max-width: 1674px;
    }
}

html, body {
    height: 100%;
    margin: 0;
}

.content {
    min-height: 100%;
    padding-top: 50px;
    padding-bottom: 100px;
}

.footer {
    height: 120px;
    margin-top: -120px;
}

.footer-institutions {
    height: 60px;
    margin-bottom: 60px;
}

.footer-institutions img {
    max-height: 40px !important;
    width: auto;
    margin: 0 7px 20px 7px;
}

.footer-biotoclin {
    height: 60px;
    background-color: var(--black);
    margin-top: -59px;
}

.footer p {
    color: var(--lightlight-grey);
    padding: 19px 0;
    margin: 0 0;
}

body {
    color: var(--black);
    font-size: 16px;
}


/* Forms: automatic shadow and color off */

select, input {
    -webkit-appearance: none;
    box-shadow: none !important;
}

:-webkit-autofill {
    color: var(--white) !important;
}

.no-spinners {
    -moz-appearance: textfield;
}

.no-spinners::-webkit-outer-spin-button,
.no-spinners::-webkit-inner-spin-button {
    -webkit-appearance: none;
    margin: 0;
}

/* Headers */

h1 {
    margin-bottom: 20px;
}

h2 {
    margin-bottom: 20px;
    font-weight: 600;
}

h3 {
    margin-bottom: 20px;
    font-weight: 500;
}


/* Links */

a {
    color: inherit;
    text-decoration: none !important;
}

a:hover, a:active, a:focus, a:visited {
    color: inherit;
    text-decoration: none !important;
}

/* other components */
.badge {
    font-weight: inherit !important;
    font-size: 100% !important;
}

.badge-db {
    border-radius: 0.5em;
    line-height: 1.5 !important;
}

/* fonts */
.pBigBold {
    font-size: 18px;
    font-weight: 600;
}

.pBold {
    font-weight: 500;
}

/* tables */
.table-hover tbody tr:hover td, .table-hover tbody tr:hover th {
    background-color: var(--lightlightlight-grey);
}


.nav-tabs .nav-item.show .nav-link, .nav-tabs .nav-link.active {
    font-weight: bold;
    background-color: var(--lightlight-grey);
    border: solid 1px var(--light-grey);
}

pre.prettyprint {
    border: solid 1px var(--light-grey);
    border-radius: 5px;
}

pre.api {
    padding: 20px;
    background-color: var(--lightlightlight-grey);
}

#tab-proteins, #tab-protein-variants, #tab-single-variant {
    border-bottom: none;
}

.nav-item:hover {
    font-weight: 600;
}


/* MARK class changes */

/* color & background */

.no-break {
    white-space: nowrap;
}

.vertical-middle {
    vertical-align: middle !important;
}

.disclaimer {
    color: #aaaaaa;
}

.disclaimer-title {
    color: #555555;
}

.color-brand {
    color: var(--main-brand-color) !important;
}

.color-white {
    color: var(--white) !important;
}


.color-brand-second {
    color: var(--second-brand-color) !important;
}

.color-brand-fhldb {
    color: #ef8784 !important;
}


.hover-color-brand:hover, .hoverColorBrand:focus, .hoverColorBrand:active {
    color: var(--main-brand-color) !important;
}

.bg-brand {
    background-color: var(--main-brand-color);
}

.bg-grey {
    background-color: var(--lightlight-grey);
}

.line-darkGrey {
    border: solid 2px var(--dark-grey);
}

.line-grey {
    border: solid 2px var(--light-grey);
}

.topLine-grey {
    border-top: solid 2px var(--light-grey);
    border-bottom: solid 2px var(--light-grey);
}

.leftRightLine-grey {
    border-left: solid 2px var(--light-grey);
    border-right: solid 2px var(--light-grey);
}

.topLine-middleLine-grey {
    border-top: solid 2px var(--light-grey);
    border-bottom: solid 1px var(--light-grey);
}

.bottomLine-grey {
    border-bottom: solid 1px var(--light-grey);
}

.bottomLine-grey2 {
    border-bottom: solid 2px var(--light-grey);
}

.underline {
    border-bottom: 2px solid;
    border-bottom-color: var(--main-brand-color);
}

.box-shadow {
    box-shadow: 10px 10px 5px var(--mediumdark-grey);
}

.pathogenic {
    background-color: var(--red);
    color: var(--white);
}

.neutral {
    background-color: var(--green);
    color: var(--white);
}

.pathogenic1 {
    background-color: var(--red-pastel);
    color: var(--black);
}

.pathogenic2 {
    background-color: var(--orange-pastel);
    color: var(--black);
}

.neutral1 {
    background-color: var(--green-pastel);
    color: var(--black);
}

.neutral2 {
    background-color: var(--lima-pastel);
    color: var(--black);
}

/* container */

.pad-container-lg {
    padding: 180px 20px 120px 20px;
}

.pad-container {
    padding: 60px 20px;
}

.pad-container-bottom {
    padding: 30px 20px 60px 20px;
}

.pad-container-top {
    padding: 120px 20px 60px 20px;
}

.pad-container-small {
    padding: 30px 20px;
}

.pad-container-small-top {
    padding: 120px 20px 30px 20px;
}

.pad-container-small-bottom {
    padding: 30px 20px 120px 20px;
}

.pad-container-small-top-bottom {
    padding: 120px 20px;
}

/* btn */

.btn {
    margin-bottom: 10px;
}

.btn:hover {
    border: 1px solid var(--main-brand-color) !important;
    background-color: var(--white) !important;
    color: var(--main-brand-color);
}

.btn-brand {
    border: 1px solid var(--white);
    background-color: var(--medium-grey) !important;
    color: var(--white);
}

.btn-brand:hover {
    background-color: var(--main-brand-color) !important;
    color: var(--white) !important;
}

.btn-shadowHover {
    border: 1px solid var(--main-brand-color);
    background-color: var(--white) !important;
    color: var(--main-brand-color);
    font-weight: bold;
}

.btn-shadowHover:hover {
    box-shadow: 5px 5px 20px rgba(0, 0, 0, 0.2);
}


/* card */

.card-brand {
    border: 2px solid var(--main-brand-color);
    transition: box-shadow 0.5s;
}

.card-brand:hover {
    box-shadow: 5px 5px 20px rgba(0, 0, 0, 0.2);
}

.card-heading {
    color: var(--white) !important;
    background-color: var(--main-brand-color) !important;
    padding: 20px;
}

.card-body {
    border: 0;
}

.card-body p {
    margin-bottom: 0;
}

.card-footer {
    border: 0;
    background-color: var(--white);
    padding-top: 0;
}


/* MARK page changes */

/* Menu */

.navbar {
    background-color: var(--main-brand-color);
    font-size: 14px !important;
    letter-spacing: 2px;
    font-weight: bold;
}

.navbar-brand {
    color: var(--white) !important;
}

.navbar li a, .navbar {
    color: var(--main-brand-color-embedded) !important;
}

.navbar li a:hover, .navbar li a:focus, .navbar li a.active {
    color: var(--white) !important;
    font-weight: bold;
}

.navbar-toggler {
    background-color: white;
}


/* welcome */

#welcome h1 {
    color: var(--white);
    font-family: Montserrat, sans-serif;
}

#welcome p.lead {
    color: var(--white);
    font-size: 24px;
}

/* software */
#software .row {
    margin-bottom: 30px;
}

#software p.header {
    font-size: 18px;
    color: var(--mediumdark-grey);
}

#report p.header {
    font-size: 18px;
    color: var(--mediumdark-grey);
}

#report p.body {
    color: var(--medium-grey);
}

.report {
    float:right;
    color:#404040;
    margin-bottom:0px;
    margin-top:15px;
}

/* interpretation */
#interpretation p.header {
    font-size: 18px;
}

#interpretation p.body {
    color: var(--mediumdark-grey);
}

#interpretation img {
    background-color: white;
    height: 150px;
    width: 150px;
}

/* contact */
#about p.header {
    color: var(--main-brand-color);
    font-size: 28px;
}

#about p.body {
    color: var(--mediumdark-grey);
}

/* institutions */

#institutions img {
    max-height: 80px !important;
    width: auto;
    margin-top: 10px;
    margin-bottom: 10px;
}

/* single & multi Query */
#singleQuery p, #multiQuery p {
    font-size: 18px;
    padding-top: 20px;
    margin-bottom: 5px;
}

/* Plots */
text {
    font: 14px sans-serif;
    fill: var(--black);
}

.bold {
    font-weight: bold;
}

.boldEmp {
    font-weight: bold;
    font-style: italic;
}

.variant {
    font-size: 16px;
    font-weight: bold;
    fill: var(--main-brand-color);
}

.axis path {
    stroke-width: 1px;
    stroke: var(--light-grey);
    fill: none;
}

.axis line {
    stroke-width: 1px;
    stroke: var(--light-grey);
}

.transparent path {
    stroke-width: 0;
    fill: none;
}


.viewport {
    stroke: var(--medium-grey);
    fill: var(--medium-grey);
    fill-opacity: 0.5;
}

div.myTooltip {
    background: var(--black);
    color: var(--white);
    font-size: 14px;
    padding: 5px 8px;
    border-radius: 10px;
    position: absolute;
    margin-top: -30px;
}

.tooltip {
    top: 10px !important;
}

/* MARK media queries */

/* small */

@media (max-width: 1200px) {

    .footer {
        height: 60px;
        margin-top: 0;
    }

    h3 {
        font-size: 140%;
    }

}	

.citation-file {
    background-color: white;
    font-size: 50px;
    padding:10px 10px;
}

.citation-quotes {
    background-color: white;
    font-size: 50px;
    padding:10px 20px;
}

.mh-400 {
    max-height:400px;
}

.alert-danger{
    margin:10px 0px;
}

.color-grey {
    color: grey;
}

.variant-box {
    border-radius:20px;
}

.plot-variant-line {
    stroke: #414141;
}

.plot-variant-line:hover {
    stroke: black;
}

.plot-variant-fill {
    fill: #414141;
}

.plot-variant-fill:hover {
    fill: black;
}